| 26.09.2020 |
17:15 |
SG Suhl/Goldlauter II | HSV Apolda II | 22 : 20 |
| 11.10.2020 |
11:30 |
HBV Jena 90 II | HSV Apolda II | 27 : 25 |
| 17.10.2020 | 17:00 | HSV Apolda II | HSV Weimar | |
| 01.11.2020 | 16:00 | HSV Apolda II | HSG Könitz/Saalfeld | |
| 07.11.2020 | 18:30 | Fortuna Großschwabhausen | HSV Apolda II | |
| 21.11.2020 | 16:30 | HSV Apolda II | SG Handball Ilmenau | |
| 28.11.2020 | 17:30 | TSV Motor Gispersleben | HSV Apolda II | |
| 05.12.2020 | 17:00 | HSV Apolda II | SG Suhl/Goldlauter II | |
| 12.12.2020 | 19:00 | HSG Könitz/Saalfeld | HSV Apolda II | |
| 09.01.2021 | 17:00 | HSV Apolda II | HBV Jena 90 II | |
| 16.01.2021 | 18:00 | HSV Weimar | HSV Apolda II | |
| 31.01.2021 | 16:00 | HSV Apolda II | Fortuna Großschwabhausen | |
| 06.02.2021 | 19:30 | SG Handball Ilmenau | HSV Apolda II | |
| 20.02.2021 | 15:00 | HSV Apolda II | TSV Motor Gispersleben |